产品货号：
Z37714
中文名称：
FADD抗体
英文名称：
Anti-FADD Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FADD Antibody |
| 指标别名 | FADD;GIG3;MORT1;Protein FADD |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | FADD |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
| 实际分子量 | 28KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FADD,Fas-Associated protein with Death Domain,is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily.The FADD gene contains 2 exons and spans approximately 3.6kb.By analysis of somatic cell hybrid panels and by fluorescence in situ hybridization,the FADD gene is mapped to 11q13.3.The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain,this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,thus,it participates in the death signaling initiated by these receptors. |
| Uniprot ID | Q61160 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Flow cytometry (FCM) 1:20 |
相关搜索：FADD抗体，FADD单抗，Anti-FADD Antibody